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Anafilaxia após ingestão de mandioca em pacientes com alergia ao látex: relato de 2 casos / Anaphylaxis after ingestion of manioc in patients with allergy to latex: reprt of 2 cases

Galvão, Clóvis Eduardo Santos; Iwai, Leo Kei; Andrade, Maria Elisa Bertocco; Yang, Ariana Campos; Kalil, Jorge; Castro, Fabio F. Morato.
Rev. bras. alergia imunopatol ; 33(2): 69-72, mar.-abr. 2010.
Artículo en Portugués | LILACS | ID: lil-565589

Objective:

To report the first cases in our country of patients with latex allergy who developed anaphylaxis with urticaria and bronchospasm after eating maníoc, suggesting the presence of cross-reactivity between these allergens.

Methods:

Latex allergy was confirmed by assessing specific IgE through in vivo (prick tests) and in vitro (ImmunoCAP) tests. 5kin tests to aeroallergens, manioc and other foods were also conducted. Allergy to manioc was confirmed with oral challenge tests. ImmunoCAP inhibition assays were performed with extract of manioc and latex to assess cross reactivity.

Results:

5kin tests to aeroallergens were negative. The skin prick tests with commerciallatex extracts were positive in both patients. Prick-to-prick with raw and cooked manioc was also positive. Both patients had positive skin tests for fresh papava and one of them for pineapple. Tests were negative for banana, kiwi and chestnut. Both had high serum specific IgE to latex. Both patients had a reaction with the open challenge test with manioc. ImmunoCAP inhibition assays revealed cross-reactivity between latex and manioc.

Conclusion:

Although previous reports have already suggested cross-reactivity between latex and manioc, this is the first report of cross reactivity between these allergens in our country, and indicates that manioc should definitely be added to the growing Iist of foods that present cross-reactívity with latex.
Biblioteca responsable: BR32.1