Adult idiopathic thrombocytopenic purpura
Maldonado, Awilda; Fernández, Adry C; Vélez García, Enrique.
Bol. Asoc. Méd. P. R
; 80(2): 44-7, feb. 1988. ilus
Artículo
en Inglés
| LILACS | ID: lil-66474
Fifty three adult patients with idiopathic thrombocytopenic purpura (ITP) were diagnosed at the University District Hospital (UDH) during the last 10 years (1976-1986). There were 33 females (62%) and 20 males (38%). All the patients were over 15 years old with a mean age of 3o years. Only 13 patients gave a history of a viral syndrome preceding the onset of symptoms. The most frequent chief complaint was petechiae and/or ecchymotic lesions. The mean initial platelet count was 10,000/mm. Bone marrow aspiration showed an increased number of megakaryocytes without platelet production in 49 patients (86%). Of the fifty three patients, 37 (70%) had a complete response to steroids. Of those not responding to steroids, 15 underwent splenectomy and 11 (73%) achieved a permanent response. Immunosupresion was prescribed in 4 patients with a 50% complete response
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