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The cost of excessive postoperative use of antimicrobials: the context of a public hospital / Consequências do uso excessivo de antimicrobianos no pós-operatório: o contexto de um hospital público

Santana, Rafael Santos; Viana, Ariane de Carvalho; Santiago, Jozimário da Silva; Menezes, Michelle Santos; Lobo, Iza Maria Fraga; Marcellini, Paulo Sergio.
Rev. Col. Bras. Cir ; 41(3): 149-154, May-Jun/2014. tab
Artículo en Inglés | LILACS | ID: lil-719492

OBJECTIVE:

To evaluate the improper use of antimicrobials during the postoperative period and its economic impact.

METHODS:

We conducted a prospective cohort study by collecting data from medical records of 237 patients operated on between 01/11/08 and 31/12/08.

RESULTS:

from the 237 patients with the information collected, 217 (91.56%) received antimicrobials. During the postoperative period, 125 (57.7%) patients received more than two antimicrobials. On average, 1.7 ± 0.6 antimicrobials were prescribed to patients, the most commonly prescribed antibiotic being cephalothin, in 41.5% (154) of cases. The direct cost of antimicrobial therapy accounted for 63.78% of all drug therapy, this large percentage being attributed in part to the extended antimicrobial prophylaxis. In the case of clean operations, where there was a mean duration of 5.2 days of antibiotics, antimicrobials represented 44.3% of the total therapy cost.

CONCLUSION:

The data illustrate the impact of overuse of antimicrobials, with questionable indications, creating situations that compromise patient safety and increasing costs in the assessed hospital. .
Biblioteca responsable: BR1.1