Análise de Interações Medicamentosas Identificadas em Prescrições da UTI Neonatal da ICU-HGU / Drug Interactions on the Neonatal Prescription at ICU-HGU
The prescription of two or more drugs is an extremely common practice, whether administered simultaneously or sequentially. Likewise, interactions can occur between drugs and other chemicals present in the environment. The aim of this study was to describe the prevalence of potential drug interactions between drugs prescribed in Neonatal ICU in a universityhospital, in addition to reporting the characteristics of these interactions and to relate the occurrence of drugs with greater number of interactions. The survey was conducted through the analysis of medical prescriptions of the Intensive Care Unit - NICU in the period April-June 2012. Forty-one patient charts were analyzed, totaling 119 prescriptions.. Sixty-one occurrences (51%) had drug interactions and 58 (49%) presented no interactions. The cases were classified according to severity severe risk to be assessed, moderate risk, risk-free and beneficial interaction. With respect to the mechanism of interaction, it was classified as pharmacokinetic and pharmacodynamic. We concluded that it the pharmacist should be integrated to the multidisciplinary health care team, as its presence is essential to minimize the frequent errors in prescriptions. The predominant profile of the interactions found in this study was the risk to be assessed and the pharmacodynamic interaction mechanism.