Evaluación de la insulinemia post carga oral de glucosa como método diagnóstico de resistencia a la insulina / Evaluation of serum insulin levels after an oral glucose load for the diagnosis of insulin resistance
To assess the distribution of seruminsulin levels at 60 and 120 minutes during OGTTs and suggest a statistical cut-off point to estimate the degree of IR. Material and
The 75th percentiles for seruminsulin levels at 60 and 120 minutes were 127 and 81 µU/mL, respectively. There was a high correlation between HOMA-IR and ISI-Composite (r = -089, p < 0.001). There was a weaker although significant correlation between HOMA-IR and ISI-Composite and insulin levels at 60 (r = 0.56 and -0.79 respectively, p < 0,001) and 120 minutes (r = 0.54 and -0.75 respectively, p < 0,001).
Conclusions:
We propose 60 and 120 min seruminsulin levels of 130 and 80 µU/mL respectively, as cut-off values for normality during OGTT in Chilean normoglycemic individuals.