Inflammatory myofibroblastic tumour arising incidentally as a polypoid lesion in the gallbladder / Tumor miofibroblástico inflamatório surgindo incidentalmente como lesão polipoide na vesícula biliar
Abrantes, Carlos Filipe C.; Silva, Mário Rui; Oliveira, Rui Caetano; Eloy, Catarina; Cipriano, Maria Augusta; Castro, Lígia P..
J. bras. patol. med. lab
; 51(6): 422-426, Nov.-Dec. 2015. tab, graf
Artículo
en Inglés
| LILACS | ID: lil-767695
ABSTRACT Inflammatory myofibroblastic tumour (IMT) is a rare mesenchymal neoplasm that usually originates from abdominal soft tissues. A female patient aged 50 years presented with a 1.2 cm gallbladder polyp. The microscopic study showed spindle cell proliferation in an edematous background rich in lymphocytes and plasma cells. Immunohistochemistry showed positivity for vimentin, smooth muscle actin, and anaplastic lymphoma kinase (ALK), and negativity for other markers. Fluorescent in situ hybridization (FISH) revealed ALK gene rearrangement. The diagnosis was IMT of the gallbladder, a unique case considering that it was identified at the early stage of development of these neoplasms.
Biblioteca responsable:
BR1.1
Texto completo
Documentos relacionados