Nonalcoholic fatty liver disease: a cohort study focusing on treatment response to nutritional counseling / A doença hepática gordurosa não-alcoólica: um estudo de coorte com foco na resposta ao tratamento com orientação nutricional
Reis, Tâmara Oliveira; Ferolla, Silvia Marinho; Lima, Maria Luiza Pereira; Fausto, Maria Arlene; Albricker, Ana Cristina Lopes; Armiliato, Geyza Nogueirade Almeida; Camelo, Clara Gontijo; Gomes, Lucas Paschoal Horta; Ferrari, Teresa Cristina Abreu; Couto, Claudia Alves.
MedicalExpress (São Paulo, Online)
; 2(2)Mar.-Apr. 2015. tab, graf
Artículo
en Inglés
| LILACS | ID: lil-776665
BACKGROUND:
Nonalcoholic fatty liver disease is the leading cause of liver pathology. The mainstay of management is weight loss. Our aim was to evaluate responses to nutritional counseling in long-term patients with this condition.METHODS:
A prospective cohort study with consecutive inclusion of 105 subjects with nonalcoholic fatty liver disease who received individualized low-calories diet counseling (1400 to 1600 kcal/day according to gender) every three months for 24 months. Weight loss of 5% or more was considered as a therapeutic response.RESULTS:
Out of 105 patients, 45 (42.9%) did not return for a second evaluation. Mean age was 55 ± 9 years, 81.6% were women and mean body mass index was 31.9 (23.8-44.9) kg/m2. Follow-up time was 6.5 (3.2-26.9) months and median appointment number was 3 (2-11). Metabolic syndrome and hypercholesterolemia were more common in women. The number of subjects who lost more than 5% weight was 5/20 (25%) at 6-months; 3/15 (33%) at 12 months; 3/18 (17%) at 18 months and 4/13 (31%) at the end of follow up. The median body weight loss at 6, 12, 18 and 24 months decreased significantly.CONCLUSIONS:
Adherence to nutritional counseling is poor in patients with nonalcoholic fatty liver disease. Only a very small proportion of patients reached the targeted body loss of weight on long term.
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BR1.1
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