Evaluate, in vitro, the photodynamic activity of four derivatives of Protoporphyrin IX by irradiation with LED 400 nm in T. rubrum.
METHOD:
Assays were subjected to irradiation by twelve cycles of ten minutes at five minute intervals.
RESULT:
Photodynamic action appeared as effective with total elimination of UFCs from the second irradiation cycle.
CONCLUSION:
Studies show that the photodynamic activity on Trichophyton rubrum relates to a suitable embodiment of the photosensitizer, which can be maximized by functionalization of peripheral groups of the porphyrinic ring.