Systemic
fungal infections are rare. In
pregnancy,
treatment is problematic because of the
risk of possible teratogenic effects of the antifungal
drugs. We present the case of a 32 year-old
woman who presented during
pregnancy with a two-month
history of painless subcutaneous nodules. Excision
biopsy of one lesion showed dematiaceous fungal
elements. Anti-fungal
treatment was deferred and the
pregnancy proceeded uneventfully. The remaining nodules were excised at the
time of
caesarean section delivery. Three weeks into the
puerperium, she developed generalised seizures and investigations indicated systemic
fungal infection with positive
cultures for
Aureobasidium spp which responded to appropriate antifungal
therapy of
flucytosine and
itraconazole.(Au)