Two cases of
cerebral malaria imported from
Guyana and
Ghana are reported. These are the first cases of
cerebral malaria diagnosed and treated in
Trinidad and Tobago since
malaria was eradicated. The management of both these cases was complicated because the
patients'
erythrocytes were
glucose-6-phosphate dehydrogenase-deficient, and by the occurrence of
blackwater fever, cerebral manifestations, renal impairment, hyperglycaemia and
thrombocytopenia. The symptoms of
cerebral malaria resolved following
treatment with
quinidine and
doxycycline and
quinidine and
clindamycin. (AU)