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Rapid SARS-CoV-2 whole genome sequencing for informed public health decision making in the Netherlands

Bas B. Oude Munnink; David F Nieuwenhuijse; Mart Stein; Manon Haverkarte; Madelief Mollers; Sandra K. Kamga; Claudia Schapendonk; Pascal Lexmond; Mark Pronk; Anne van der Linden; Theo Bestebroer; Irina Chestakova; Ronald J. Overmars; Stefan van Nieuwkoop; Richard Molenkamp; Annemieke van der Eijck; Corine GeurtsvanKessel; Harry Vennema; Adam Meijer; Andrew Rambaut; Jaap van Dissel; Reina Sikkema; Aura Timen; Marion Koopmans.
Preprint en Inglés | PREPRINT-BIORXIV | ID: ppbiorxiv-050633
SARS-CoV-2 is a novel coronavirus that has rapidly spread across the globe. In the Netherlands, the first case of SARS-CoV-2 has been notified on the 27th of February. Here, we describe the first three weeks of the SARS-CoV-2 outbreak in the Netherlands, which started with several different introductory events from Italy, Austria, Germany and France followed by local amplification in, and later also, outside the South of the Netherlands. The timely generation of whole genome sequences combined with epidemiological investigations facilitated early decision making in an attempt to control local transmission of SARS-CoV-2 in the Netherlands.