Biblioteca Virtual en Salud

In this report, we provide summary estimates, from publications and reports, of vaccine efficacy (VE) for the COVID-19 vaccines that are being rolled out on a global scale. We find that, on average, the efficacy against any disease with infection is 85% (95% CI 71 - 93%) after a fully course of vaccination. The VE against severe disease, hospitalization or death averages close to 100%. The average VE against infection, regardless of symptoms, is 84% (95% CI 70 - 91%). We also find that the average VE against transmission to others for infected vaccinated people is 48% (95% CI 45 - 52%). Finally, we prove summary estimates of the VE against any disease with infection for some of the variants of concern (VOC). The average VE for the VOC{gamma} (P1) is 61% (95% CI 43 - 73%). The average VE for the VOC (B.1.1.7), {beta} (B.1.351), and{delta} (B.1.617.2) after dose 1 are 48% (95% CI 44 - 51%), 35% (95% CI -11 - 62%), and 33% (95% CI 21 - 43%), respectively. The average VE for the VOC (B.1.1.7), {beta} (B.1.351), and{delta} (B.1.617.2) after dose 2 are 85% (95% CI 25 - 97%), 57% (95% CI 14 - 78%), and 78% (95% CI 28 - 93%), respectively.