Absence of SARS-CoV-2 antibodies in pre-pandemic plasma from children and adults in Vietnam
Chau Van Vinh Chau; Le Nguyen Thanh Nhan; Lam Anh Nguyet; Nguyen Thi Kha Tu; Nguyen Thi Thu Hong; Dinh Nguyen Huy Man; Dinh Thi Bich Ty; Le Nguyen Truc Nhu; Lam Minh Yen; Truong Huu Khanh; Ngo Ngoc Quang Minh; Nguyen Thi Han Ny; Danielle Anderson; Lin-Fa Wang; H. Rogier van Doorn; Nguyen Thanh Hung; Tran Tan Thanh; Guy Thwaites; Le Van Tan.
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| PREPRINT-MEDRXIV | ID: ppmedrxiv-21260379
We tested pre-pandemic (2015-2019) plasma samples from 148 Vietnamese children, and 100 Vietnamese adults at high risk of zoonotic infections, for antibodies against SARS-CoV-2 nucleocapsid and spike proteins. None was positive, indicating no prior serological cross-reactivity with SARS-CoV-2 that might explain the low numbers of COVID-19 in Vietnam.
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