Multisystem Inflammatory Syndrome in Children: sectional study of cases and factors associated with deaths during COVID-19 pandemic in Brazil, 2020 / Síndrome inflamatorio multisistémico pediátrico: estudio seccional de casos y factores asociados a las muertes durante la pandemia COVID-19 en Brasil, 2020 / Síndrome inflamatória multissistêmica pediátrica: estudo seccional dos casos e fatores associados aos óbitos durante a pandemia de COVID-19 no Brasil, 2020
de Almeida Relvas-Brandt, Laís; Gava, Caroline; Sindeaux Camelo, Fernanda; Bertollo Gomes Porto, Victor; Fernandes Santos Alves, Ronaldo; Santos Correa Da Costa, Marcela; Maria Deotti Carvalho, Sandra; Madeleine Ikeda do Carmo, Greice; Fontana Sutile Tardetti Fantinato, Francieli; Yoshito Wada, Marcelo; Myrna Meneses Brandão e Mendes, Yluska; Gonçalves Vieira, Martha; Bugarin Steenhouwer, Roselle; Magalhães Pereira Castello Branco, Klebia; Câmara dos Santos, Maria Verônica; Romero Rivera, Ivan; Nicoloso, Luiz Henrique; Palazzi Safadi , Marco Aurelio; Maria de Assis, Dalva.
Preprint
en Portugués
| PREPRINT-SCIELO | ID: pps-2968
Objective:
To describe the clinical-epidemiological profile of Multisystem Inflammatory Syndrome in Children (MIS-C) cases and to identify factors associated with MIS-C deaths in Brazil, 2020.Methods:
Cross-sectional study, based on MIS-C national monitoring database in Brazil, 2020. Simple and multiple logistic regression was performed to estimate crude and adjusted odds ratios (OR).Results:
The median age of cases (n=652) was 5 years, 57.1% were male, 52.0% were brown race/color and 6.4% died. The odds of death was greater among those who presented O2 saturation <95% (ORa=4.35 95%CI 1.69;11.20) and altered result of urea (ORa=5.18 95%CI 1.91;14.04); lower in the absence of cutaneous lesion such as rash (ORa=0.23 95%CI 0.09;0.62), with the use of anticoagulants (ORa=0.32 95%CI 0.12;0.89) and of immunoglobulins (ORa=0.38 95%CI 0.15;1.01).Conclusion:
Fatality rates was higher among cases that presented O2 saturation<95% and altered urea, and lower among those with cutaneous lesion, who used immunoglobulins and anticoagulants.
Biblioteca responsable:
BR1.1
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