Osteonecrosis of
hip is a pathological condition that leads to collapse of the
femoral head, & the need for
total hip replacement (THR).
Research has shown that at the cellular level there is decrease in osteoblastic activity & the local
mesenchymal stem cells (MSC)
population that leads to
osteonecrosis of
femoral head (ONFH). Cellular
therapy could thus be used to improve the local cellular
environment. Th is can be achieved by implanting
bone marrow, containing osteogenic precursors into the necrotic lesion of the
femoral head.