A Rare Case of Acute Psychosis as an Isolated Manifestation of Extrapontine Myelinolysis.

Sulaiman, Wan Aliaa Wan; Hoo, Fan Kee; Basri, Hamidon; Hasan, Shariful; Lim, Sazlyna Mohd Sazlly; Foo, Yoke Loong; Ching, Siew Mooi; Vasudevan, Ramachandran; Mohamed, Mohd Hazmi; Hashim, Hasnur Zaman

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A Rare Case of Acute Psychosis as an Isolated Manifestation of Extrapontine Myelinolysis.

Sulaiman, Wan Aliaa Wan; Hoo, Fan Kee; Basri, Hamidon; Hasan, Shariful; Lim, Sazlyna Mohd Sazlly; Foo, Yoke Loong; Ching, Siew Mooi; Vasudevan, Ramachandran; Mohamed, Mohd Hazmi; Hashim, Hasnur Zaman.

Br J Med Med Res ; 2014 June; 4(18): 3554-3560

Artículo en Inglés | IMSEAR | ID: sea-175276

Aims and

Background:

Central pontine myelinolysis (CPM) and extrapontine myelinolysis (EPM) are recognized as osmotic demyelination syndrome (ODS). ODS is pathologically characterized by non-inflammatory demyelination of several brain structures with sparing of axons. This condition is usually associated with overzealous correction of hyponatraemia. Acute psychosis as the sole clinical manifestation is extremely rare. Presentation of Case Hence, we report an interesting case of a middle-aged man who was diagnosed with EPM, following rapid correction of hyponatraemia and subsequently developed acute psychosis. He made a good recovery with supportive treatment alone. Discussion and

Conclusion:

The possibility of psychosis as a manifestation of ODS, particularly in patients with recent correction of hyponatraemia. The rate of correction of plasma sodium level is the key point for preventing ODS and its complications.

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Formato de exportación:

A Rare Case of Acute Psychosis as an Isolated Manifestation of Extrapontine Myelinolysis.

Background:

Conclusion: