Hemostatic system is designed to maintain
blood in a fluid
state yet provide important defenses against
bleeding when
injury occurs to the vessel. During
surgery ,
patients are exposed to
hemostatic stress causing
complications of either
hypercoagulability or
hemorrhage . The
goal of the present study was to describe the clotting changes in
patients who underwent major surgeries especially procoagulant mechanisms.
Methods: 30
patients belonging to both sexes
who were undergoing
surgery for various reasons were included in the study. Tests to assess the integrity of
hemostatic system were conducted.
Results: Analysed and expressed in mean and SD. There was a significant (p<0.05) difference in the
hemostatic parameters like
bleeding time , clotting
time, thrombin time ,
platelet count and
fibrinogen concentration between the preoperative and
postoperative periods .