Proton pump inhibitors (PPIs) are the most widely prescribed class of
gastrointestinal drugs as they have minimal side effects and few significant
drug interactions, and are generally considered safe for long-term
treatment. The
proton pump inhibitors such as
omeprazole,
esomeprazole,
pantoprazole,
lansoprazole and
rabeprazole have quite
similar efficacy and
potency. Current study was carried out at Jessore district in
Bangladesh to investigate the current status of most commonly prescribed PPIs in terms of their generation,
gender variation, age categorization and their preferred route of
administration as well. However,
esomeprazole was used by top most 70%
patients, followed by 20%, 6%, 3% and 1% for
omeprazole,
pantoprazole,
rabeprazole and
dexlansoprazole respectively. 75%
prescriptions were prescribed for oral route of
administration. 55%
male and 35% of 35-50 years
aged patients are suffering from
peptic ulcer diseases and uses PPIs for healing process. During
proton pump inhibitor therapy, it was observed to have
nausea of 30% and
vomiting for 28%
patients as a major side effect. This study reveals that the new generation PPIs becomes more popular for the
treatment of gastric disorders among people of Jessore city,
Bangladesh.