Fenoxaprop-P-ethyl (FPPE) is a phenoxy
herbicide and exerts its herbicidal action by interfering with
fatty acid biosynthesis through inhibition of
acetyl-CoA-carboxylase in
plant chloroplast and thereby hampering
fatty acid synthesis. It also inhibits this
enzyme in the mammalian
liver and has produced reversible hepatic
toxicity in
laboratory studies.
Poisoning with this
herbicide is uncommon, and
herbicide product appears to be safe in
patients with an acute
self-
poisoning, particularly in comparison with other
herbicides and causing few clinical features. Here, we
report the case of a 35-year-old
male patient presented with FPPE
poisoning. He came with an altered sensorium and later on developed acute
myocardial infarction. Even after appropriate management, the
patient deteriorated and succumbed.