Background:
Patients with
Human Immunodeficiency Virus (
HIV)
infection are predisposed to numerous
opportunistic infections due to decreased
cell mediated immunity,
Tuberculosis being most common. Low
CD4 count is associated with low
immunity and higher
risk of
tuberculosis.
Methods:
Author conducted a
retrospective study in the department of
Pulmonary medicine in a
tertiary care teaching hospital during January to December 2017. Author collected data of all the
patients with
HIV diagnosed with
Tuberculosis from the
ART centre. Author collected demographic details including age,
sex, symptoms at presentation, details of
diagnosis of TB including type of
tuberculosis, CBNAAT results,
CD4 count at the
diagnosis of TB, details of
ART therapy and ATT
therapy and outcomes of
treatment.
Results:
Eighty one
patients with
HIV-TB co-
infection were included in the study.
Males (70.37%) were more affected than
females. Mean age of the study group was 39.97� years. Sixty one
patients (75.4%) were diagnosed with
Pulmonary Tuberculosis and 20 (24.6%)
patients were diagnosed with extra pulmonary TB. Mean
CD4 counts of the cohort was 226�0/祃. Eighty percent of
patients developed
Tuberculosis with
CD4 count <250/祃.
Conclusions:
Author found in this study higher proportions of
tuberculosis (80.2%) in
patients with
HIV infection with
CD4 count <200/祃. Author also found higher proportion of pulmonary Koch抯 in
patients with low
CD4 count (CD4 <200/祃).