Background: Iron deficiency anaemia in
pregnancy is a common medical problem throughout
India with the
burden of disease impacting on both
mother and the
newborn . It is also responsible for increased
incidence of
premature births ,
low birth weight babies and high
perinatal mortality . Intravenous
iron sucrose and oral
iron therapy are the primary
therapeutic modalities for management of
iron deficiency anaemia during
pregnancy , but its
efficacy during
pregnancy is still a matter of argument among
healthcare personnel . Therefore the objective of this study is to compare the effect of oral
iron and intravenous
iron sucrose on
hemoglobin and other
blood indices among pregnant
females with
iron deficiency anemia .
Methods: Randomized
clinical trial was conducted among 400
females between 20 to 34 weeks
gestation with
iron deficiency anemia who were managed either with oral ferrous sulphate or intravenous
iron sucrose therapy . Z test was used for
statistical analysis for significance with 95%
confidence interval . The
hemoglobin and
blood indices levels before and after initiating
treatment in both groups were compared.
Results: Intravenous and oral; both the
treatments were associated with increment in
hemoglobin but this rise was significantly more in the intravenous group than in oral. Comparing participants with low pretreatment
hemoglobin among both groups, participants in the intravenous group were better benefited than oral due to respective
treatment .
Conclusions: Intravenous
iron therapy is much effective in correcting
iron deficiency anemia in
pregnancy than oral
iron therapy . It restores
iron stores more promptly. Also intravenous
iron is better tolerated compared to oral
iron .