Biblioteca Virtual en Salud

The present study was conducted to detect the status of anthelmintic resistance of commonly used anthelmintic drugs viz. fenbendazole and morantel against gastrointestinal nematodes in sheep of village Badhra, district Charkhi dadri, Haryana. Forty five sheep with egg per gram of more than or equal to 150 were divided into three groups i.e. S1, S2 and S3 of 15 animals each. Group S1 and S2 were treated with fenbendazole @ 5 mg/kg b.wt. orally and morantel @ 10 mg/ kg b.wt. orally, respectively. Group S3 served as untreated control. Faecal samples were collected on the day of treatment (zero day) and 12th day post treatment (PT), from sheep of all groups and individual FEC were determined by the modified McMaster technique. Pooled faecal cultures were made to recover infective larvae on day 0 and 12 PT. Results revealed that fenbendazole (S1) reduced the FEC by 74.77% on 12th day PT with upper and lower confidence levels as 86.41% and 53.15%, respectively indicating moderate anthelmintic resistance. Morantel (S2) caused 49.84% reduction in FEC with upper and lower confidence levels as 65.04% and 28.04%, respectively indicating severe anthelmintic resistance. Thus, the present study revealed presence of cross anthelmintic resistance against fenbendazole and morantel in Haemonchus population in sheep of unorganized sector in Haryana as the post-treatment coproculture showed only Haemonchus contortus larvae