Invasive fungal infections in
critically ill patients are associated with increased
morbidity and
mortality.
Candida species are among the most common causes of nosocomial
bloodstream infections and of invasive
infections in
intensive care units (ICUs). The high
mortality mandates early identification of
invasive candidiasis which is vital to initiate appropriate and timely
treatment and improve outcomes. Delaying the initiation of
treatment could result in an increase in
mortality which can be avoided by usage of more
rapid diagnostic techniques. There are multiple
diagnostic tests including
culture and non-
culture tests like 1,3-β-D-
glucan and newer
techniques like
MALDI-TOF which are available to
diagnose candidemia but each with their drawbacks. Additionally, there are various guidelines like IDSA and ESCMID on
treatment which aim to minimize
death, late
complications from deep-seated
candidiasis and rise of
drug- resistant
Candida strains. Through this
consensus statement prepared by a panel of experts, all of whom are senior intensivists,
infectious disease specialists and microbiologists, we aim to
address the major aspects of management of
invasive candidiasis in the Indian
population as per the authors
opinions, backed by published evidence and supported by the latest
clinical guidelines.