Background: The
incidence of
lymphoproliferative disorders has increased in many parts of the world. Newer subtypes have been identified by the new
WHO classification . Accurate subtyping of
lymphomas is crucial for prompt
treatment . Objective of the study was to assess the clinicopathological pattern of lymphoproliferative
diseases diagnosed in Rajagiri
hospital over a period of 3 years.
Methods: A
retrospective study on all
patients who were diagnosed with
lymphoma in Rajagiri
hospital during January 2016 to December 2018 was conducted and the data were reviewed and analyzed.
Results: A total of 151
patients were included in the study. Majority of the subjects (63%) were
males . The predominant
age group affected was 61-80 years. Mean
age group was 58.46 years (SD=19.05 years). Most common presenting symptom was painless
lymphadenopathy . B symptoms were seen in 18% of subjects and was found to be more commonly associated with B
cell Non-Hodgkin lymphoma. Most common
lymph node involved was cervical
lymph node , while the most common extra nodal site was
bone marrow . Most common
lymphoproliferative disorder was
Diffuse large B cell Lymphoma .
Lymph node involvement was found in 74% of
patients , while
hepatomegaly and
splenomegaly were seen in 11% and 18.5% of
patients . 20% of
patients had
secondary bone marrow involvement. 8
patients developed recurrent lesions involving other organs.
Conclusions: Clinicopathologic patterns of
lymphoproliferative disorders vary across various regions. A proper
understanding of demographical distribution of
lymphomas is very essential, as it can provide valuable clues for accurate
diagnosis and
treatment .