Anticholinergic medications are frequently prescribed for gastrointestinal and genitourinary
spasms.
Psychosis, when present, results from
anticholinergic overdose or
toxicity. In the
literature,
anticholinergic-induced
psychosis at
therapeutic doses in
patients with normal
cognition is extremely uncommon. Here, we describe the case of a 28-year-old
female who presented with auditory and visual hallucinations, stereotypy, and agitation after receiving a single
intramuscular injection of 20 mg
hyoscine butylbromide for
dysmenorrhea. Even though it is rare for a
therapeutic dose of
hyoscine butylbromide to cause
psychosis, clinicians should maintain a high index of suspicion and be cautious when administering or prescribing
anticholinergics.