The mean age of PD patients was 68.4 years ± 10.64 (range 46–82) and in the control group was 66.36 ± 5.22 (range 64–68). The average disease duration in patients with PD was 6.7 ± 2.8 years (range 2–10 years). The mean best?corrected visual acuity in PD was 20/26 and 20/20 in controls, with P = 0.0059, which was significant. Significant difference was also found in the contrast sensitivity between both groups. Structural differences in the central macular thickness (P = 0.0001), subfield thicknesses in the superior (P = 0.003), inferior (P = 0.001), nasal (P = 0.004), and temporal subfields (P = 0.017) was seen. Severe thinning of the ganglioncell layer was seen in PD patients (P = 0.000) as well as of the nerve fiber layer (P = 0.004). Peripapillary retinalnerve fiber thickness measured showed significant thinning in superotemporal (P = 0.000), superonasal (P = 0.04), inferonasal (P = 0.000), inferotemporal (P = 0.000), nasal (P = 0.000), and temporal quadrants (P = 0.000).
Conclusion:
Visual dysfunction was observed in patients with PD along with structural alterations on OCT, which included macular volumes, ganglioncell layer, and peripapillary retinalnerve fiber layer.