Eight hundred sixteen healthy Thaiadultsaged between 21-70 years were recruited in the present study. SerumIGF-I was measured by using immunochemiluminescent (ICMA; Roche, USA). Subjects were recorded by their age and gender groups. Data were presented in mean and +/- 2 standard deviation (SD). Correlation analysis between serumIGF-I and physical parameters including sex, age, weight, height, and body mass index (BMI) was also made.
RESULTS:
The present study demonstrated normal reference range of serumIGF-I by using mean +/- 2 SD value. The well-known age dependency of serumIGF-I levels was also revealed. Levels decreased with increasing age in both genders. The mean value of serumIGF-I was slightly higher in women at the age of 30-40 years compared with men in the same age group, but not statistically insignificant. In addition, serumIGF-I was found to correlate directly with the height and negatively with BMI. However, age-adjusted IGF-I level did not show correlation with these physical parameters.