Neuroprotective effects of vitamin E in cold induced cerebral injury in guinea pigs.
Badhe, Prerna; Thorat, Jayant; Diyora, Batuk D; Mamidanna, Ravikrishna; Sayal, Parag; Badhe, Suvarna; Sharma, Alok K.
Indian J Exp Biol
; 2007 Feb; 45(2): 180-4
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| IMSEAR | ID: sea-56371
Significant reduction in hemorrhage (10 v/s 13), necrosis (2 v/s 4), cavitations (7 v/s 13), neuronal degeneration, perivascular and parenchymal inflammatory infiltrate (7 v/s 11) were observed in Vitamin E treated cold induced head injury in guinea pigs, evaluated post injury using the modified Benderson's scale. The results suggest that Vitamin E is highly effective in promoting clinical and histopathological recovery in cold induced head injury in guinea pigs.
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