t-BHP induced
oxidative stress and Ca2+ function impairment in fresh
hepatocytes was studied in order to understand its
role in cytotoxicity. Viability of
hepatocytes by the release of
lactate dehydrogenase and methyl thiazoletetrazolium reduction
method alongwith
malondialdehyde formation indicated
oxidative stress in the hepatotoxic action of t-BHP.