Serum fibrin/
fibrinogen degradation product (FDP) was studied in 64
patients of
menorrhagia without any organic cause in addition to 24 healthy
women by Thrombo - Wellcotest HA - 13 Kit (Wellcome,
England).
Serum FDP levels were found to be less than 10 micrograms/ml in
healthy subjects, whereas in idiopathic
menorrhagia it was more than 10 micrograms/ml in 59.34%
patients. Semi-quantitative estimation of FDP in 14
patients of idiopathic
menorrhagia indicated a positive correlation between duration of
bleeding and FDP levels.
Bleeding appears to be due to increased fibrinolytic activity in
uterus secondary to
plasminogen activator. Such
patients are likely to be benefitted with anti-
fibrinolytic agents.