We
report the case of a three year old
female child with combined occurrence of
von Willebrand's disease and
factor XIII deficiency, an extremely rare combination. The
patient presented with prolonged
bleeding following cuts and
wounds. Clot
solubility test using 5M
urea was positive.
Platelet aggregation using
ristocetin was reduced, which corrected on adding normal
plasma. Aggregation with other
agonists was normal. We discuss the clinico- hematological profile of the case. Only one such case has been reported in
literature in the past to the best of our
knowledge.