During the last three decades, a better
understanding of
viral replication and
disease states caused by
viral infections have led to the development of newer
antiviral agents with enhanced activity and better tolerability. This
review focuses on newer systemic and topical
antiviral agents that are used in
treatment of herpes
viruses including
herpes simplex type-1 (
HSV-1) and type-2 (
HSV-2),
varicella-zoster virus (VZV) and
cytomegalovirus CMV) as well as the
human papilloma virus (HPV). Included in this article are the agents
famciclovir, penciclovir,
valganciclovir,
imiquimod, docosanole and brivudin.