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Seroprevalence of hepatitis B and C virus markers among blooddonors in Rio de Janeiro, Brazil, 1998-2005

Andrade, Ana F. B. ; Oliveira-Silva, Michelle ; Silva, Suely G. C. ; Motta, Iara J. F. ; Bonvicino, Cibele R. .
Mem Inst Oswaldo Cruz ; 101(6): 673-676, sep. 2006. graf, tab
Artículo en Inglés | TXTC | ID: txt-22121
The prevalence of infection by hepatitis B (HBV) and C (HCV) viruses varies among geographical regions. Inorder to determine the prevalence of HBV and HCV infection in voluntary blood donors we evaluated the prevalenceof HBsAg, anti-HBc, and anti-HCV markers of 128,497 blood donor samples collected from 1998 to 2005 in the stateof Rio de Janeiro. These markers were analyzed by immunoenzymatic tests, as determined by the Ministry of Health.Data were obtained from the Sorology Laboratory of the Hemoterapy Service of the Instituto Nacional de Cƒncer,Rio de Janeiro. Overall prevalence estimates were 0.27% for HBsAg, 3.68% for anti-HBc, and 0.90% for anti-HCV.There was a significant decrease in the overall prevalence of HBsAg (from 0.36 to 0.14%) and anti-HBc (from 6.12to 2.05%) in the period encompassed between 1998-2005. Similarly, there was a decline in anti-HCV prevalencerates in Brazilian blood donors, from 1.04% in 1998 to 0.79% in 2004, with an increase of HCV prevalence to 1.09%in 2005. These prevalence estimates were higher than those found in other countries, indicating high rates ofinfection by HBV and HCV and a persistent risk of HBV and HCV transmission by transfusion.(AU)
Biblioteca responsable: BR440.1
Ubicación: BR440.1