Here we evaluated the effects of the ileal denervation with BT in rats with SBS by verifying the body weight variation and intestinal morphological parameters. Four groups with 6 animals each were submitted to enterectomy with an ileal injection of saline (group E) or BT (group EBT). Control groups were submitted to simulated surgery with an ileal injection of BT (group BT) or saline (group C control).
Results:
We observed that the treatment of the remaining ileum with BT completely reversed the weight loss associated to extensive small bowel resection.
Conclusion:
This may provide a new promising approach to the surgical treatment of SBS.(AU)