Use of the anabolic steroid nandrolone decanoate associated to strength training in Wistar rats / Uso do esteróide anabólico decanoato de nandrolona associado ao treinamento de força em ratos Wistar
Andreato, Leonardo Vidal; Esteves, João Victor Del Conti; Almeida, Felipe Natali; Ribeiro, Tatiane Aparecida da Silva; Barrena, Helenton Cristhian; Peres, Sidnei Barnabé; Moraes, Solange Marta Franzói de.
Acta Sci. Biol. Sci.
; 35(2): 283-291, apr.-june.2013. tab, graf
Artículo
en Inglés
| VETINDEX | ID: vti-28182
Anabolic steroids have been constantly used among athletes and physically active individuals. Adverse effects of such use are reported in the literature. However, little is known about the effects of anabolic steroid use associated with strength training. Thus, this research aimed to identify possible morphophysiological alterations in Wistar rats treated with the anabolic steroid nandrolone decanoate and submitted to strength training. Twenty Wistar rats were divided in four groups sedentary control (SC), sedentary hormone (SH), trained control (TC) and trained hormone (TH). After the experimental protocol period, animals were killed and body weight, adiposity, renal and hepatic injury markers, plasmatic lipid profile, glycemia, and insulinemia were determined. The experimental conditions strength training and nandrolone decanoate (isolated or associated) were positively correlated to a reduction on visceral and subcutaneous adipose tissue. The association of strength training with nandrolone decanoate was the most effective condition to increase muscle mass. Heart and kidneys weights, aspartate aminotransferase (AST) and high density lipoprotein (HDL) concentration were also negatively modified. The data demonstrated effects of anabolic steroids in body composition, with better results when associated with strength training, but collateral effects were observed.(AU)
Biblioteca responsable:
BR68.1
Ubicación: BR68.1
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