Cerebral amyloid angiopathy-related
inflammation (CAA-RI) is a rare
encephalopathy characterized by the coexistence of a perivascular inflammatory reaction in
patients with
cerebral amyloid angiopathy. CAA-RI
diagnosis is challenging as its final
diagnosis requires invasive
procedures such as
autopsy or
brain biopsy. Therefore,
multimodal imaging approaches with clinical considerations are essential for the probable
diagnosis of CAA-RI. In particular, in the case of CAA-RI presented with uncommon clinical symptoms, the need for imaging in
diagnosis is further highlighted by difficulties of clinical approaches. Herein, we
report a case of CAA-RI with unusual clinical manifestation diagnosed using
multimodal imaging including
magnetic resonance imaging (MRI) and
amyloid positron emission tomography-computed tomography (
PET-CT).
Multimodal imaging approaches using adequate MRI sequences and
PET-CT scans could facilitate the
diagnosis of CAA-RI without requiring invasive pathological confirmation.