Cutaneous
squamous cell carcinoma is the second most common
tumor in
humans, and its
incidence is increasing. In cutaneous
squamous cell carcinoma,
lymph node and distant
metastases are rare, and
bone invasion in the
lower limbs is uncommon. A 67-year-old
male presented with a solitary erythematous plaque on the fifth
toe, accompanied by swelling. A shave
biopsy was performed. The
diagnosis of
bone-invaded
squamous cell carcinoma with aggressive
behavior was made by combining the histopathological, immunohistochemical
staining, and
magnetic resonance imaging results.
Mohs micrographic surgery was performed to remove the
skin lesion and
tumor-invaded
bone. However, 2 months later,
squamous cell carcinoma relapsed in the same area. After confirming the absence of
lymph node metastasis, additional
treatment, including ray
amputation, was performed.
Adjuvant radiotherapy was not administered. We present a rare case of
squamous cell carcinoma that relapsed after
Mohs surgery and was subsequently treated with ray
amputation.