Objective@#This study aimed to explore the
mediating effects of
cancer -related dysfunctional
beliefs regarding
sleep and intolerance of
uncertainty on the effect of
depression ,
insomnia , and
anxiety on
fear of progression (FoP). @*
Methods @#We retrospectively reviewed
medical records of
patients with
cancer who visited the
Sleep Clinic for
cancer patients in Asan Medical Center for the first
time between December 2021 and March 2022. Data collected included age,
sex , types of
cancer , staging, current
treatment modalities, and
history of
surgical procedures . In addition, psychological symptoms were rated using the
Insomnia Severity Scale (ISI),
Patient Health Questionnaire –9 items (
PHQ-9 ),
State subcategory of the
State and Trait of
Anxiety Inventory (STAI-S), Short form of
Fear of Progression
Questionnaire ,
Cancer -related Dysfunctional
Beliefs about
Sleep scale (C-DBS), single item of
pain and
fatigue , Connor Davidson
Resilience Scale 2-item (CD-RISC2), and Intolerance of
Uncertainty –12 (IUS-12). The predictive variables for FoP were determined by
linear regression analysis . @*Results@#The FoP was significantly correlated with age (r=-0.289), ISI (r=0.178),
PHQ-9 (r=0.703), STAI-S (r=0.377),
fatigue (r=0.452), CD-RISC2 (r=-0.270), IUS-12 (r=0.585), and C-DBS (r=0.427, all p<0.01). A
mediation analysis showed that intolerance of
uncertainty and dysfunctional
beliefs about
sleep mediated the relationship of FoP with
insomnia ,
depression , or
anxiety . @*Conclusion@#Psychological support for intolerance of
uncertainty and
cancer -related dysfunctional
beliefs about
sleep in
patients with
cancer may be beneficial to reduce their FoP.