Nonalcoholic fatty liver disease (
NAFLD) has become the most common chronic
liver disease in the world, and it is also one of the main causes of
liver cirrhosis and
hepatocellular carcinoma, so it is particularly important to curb the development and progression of
NAFLD in a timely manner. However, due to its complex pathogeneses, there are currently no effective
methods for radical
treatment. As a new generation of
probiotics,
Akkermansia muciniphila (Akk
bacteria) can improve metabolic disorders of the body, and more and more studies have shown that Akk
bacteria have a potential
therapeutic effect on
metabolic diseases, especially
NAFLD. Therefore, this article briefly reviews the mechanism of action of Akk
bacteria in
NAFLD, in order to provide new ideas for improving the
treatment of
NAFLD and creating new
therapies.