Angiogenesis,the formation of new
blood vessels from the development of existing
capillaries or posterior capillar)'
veins,is a key event in various physiological and pathological en-vironments.In recent years,the
role of
endothelial cell metabo¬lism in
pathological angiogenesis has attracted much
attention.More and more studies have shown that endothelial
angiogenesis switches and
pathological angiogenesis are regulated by key fac¬tors of
energy metabolism.'Hie unique
glycolysis properties of
endothelial cells are essential for
cell proliferation,migration and response to environmental changes.In this
review, we provide an overview of recent
research on
endothelial cell energy metabolism and summarize and discuss the potential
therapeutic strategies u- sing
endothelial cell metabolism to provide some reference for dnjg development targeting
endothelial cell metabolism.