Averrhoa Carambola L. Roots DMDD alleviates myocardial injury in diabetes mellitus mice by regulating ROS-mediated autophagy pathway / 中国药理学通报
Jing MA; De-Lun HUANG; Yan-Ping ZHOU; Liu-Ting HOU; Ya-Kun LI; Jing ZHONG; Xiao-Jie WEI; Ya-Ni WU.
Chinese Pharmacological Bulletin
; (12): 823-827, 2021.
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en Zh
| WPRIM | ID: wpr-1014442
Aim To evaluate the protective effect of Averrhoa Carambola L. Roots DMDD alleviating myocardial injury in diabetes mellitus (DM) mice and its mechanism. Methods SD mice were given high-glucose-high-fat diet combined with streptozotocin to induce DM model, and were administered with DMDD. The fasting blood glucose (FBG) was recorded. The left ventricular end-diastolic pressure (LVEDP), left ventricular systolic pressure (LVSP), maximum upstroke velocity of left ventricular pressure (+ dp/dt
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