Obstructive sleep apnea (OSA) is a common
sleep disordered breathing disorder. As a major global
public health problem, untreated OSA can
lead to a variety of adverse
health outcomes, including various cardiovascular and
cerebrovascular diseases, metabolic disorders, and
psychiatric disorders such as
anxiety and
depression. Traditional OSA
therapies such as positive
airway pressure (PAP),
weight loss, oral appliance, upper
airway surgery, and postural
therapy focus on the anatomical factors of OSA. However, the pathogenesis of OSA is heterogeneous, and non-anatomical factors also
play an important
role in most
patients. Although there is no
drug with exact
efficacy for the
treatment of OSA, with the deepening
understanding of the pathophysiological mechanism of OSA, more and more clinical studies are devoted to the study of
drug treatment of OSA and its
complications, and a series of results have been achieved. The following is a
review of the relevant studies on
drug treatment of OSA in recent years, hoping to provide
literature support and theoretical basis for
future research on
drug treatment of OSA.