Crohn's disease (CD) is a chronic relapsing and remitting inflammatory
disease of the
gastrointestinal tract. CD is rare in
Taiwan and other
Asian countries, but its
prevalence and
incidence have been steadily increasing. A steering committee was established by the
Taiwan Society of
Inflammatory Bowel Disease to formulate
statements on the
diagnosis and management of CD taking into account currently available evidence and the
expert opinion of the committee. Thorough clinical, endoscopic, and histological assessments are required for accurate
diagnosis of CD. Computed
tomography and
magnetic resonance imaging are complementary to endoscopic evaluation for
disease staging and detecting
complications. The
goals of CD management are to induce and maintain remission, reduce the
risk of
complications, and improve
quality of life.
Corticosteroids are the mainstay for inducing re-mission. Immunomodulating and
biologic therapies should be used to maintain remission.
Patients should be evaluated for
hepatitis B virus and
tuberculosis infection prior to
treatment and receive regular
surveillance for
cancer. These
consensus statements are based on current local evidence with consideration of factors, and could be serve as concise and practical guidelines for supporting clinicians in the management of
patients with CD in
Taiwan.