PURPOSE: To elucidate
risk potentiality of frontline
radiotherapy associated
cataracts in primary ocular adnexal
mucosa-associated lymphoid tissue lymphoma (OAML).
METHODS: Data from eight consecutive
patients of 41 total OAML
patients who had undergone
cataract surgery after frontline
radiotherapy were analyzed.
RESULTS: The median
patient age was 46 years (range, 36 to 69 years). The median total
radiation dose was 3,780 cGy (range, 3,060 to 4,500 cGy), and the mean duration from
radiation irradiation to
cataract surgery was 36.60 +/- 8.93 months. Preoperative lens opacification was primarily at the posterior lens subcapsule, and best-corrected
visual acuity (BCVA) was 0.43 +/- 0.21.
Patients underwent the
phacoemulsification surgical procedure with posterior chamber
intraocular lens insertion. The average BCVA improved to 0.90 +/- 0.14 after
cataract surgery . Two
patients underwent posterior continuous curvilinear
capsulorhexis , and one had posterior
capsule rupture . For posterior
capsule opacification (PCO), three
patients received NdYAG laser
posterior capsulotomy after the initial
surgery , and one
patient is currently under consideration for
laser posterior capsulotomy .
CONCLUSIONS: Radiotherapy increased posterior subcapsule opacification at a relatively young age in primary OAML.
Phacoemulsification was a manageable
procedure without severe
complications , and final visual outcomes were good. However, because after-
cataracts progressed earlier than did senile
cataracts , close follow-up should be considered for PCO management.