Vasculitis is a heterogeneous group of
diseases that destroy
blood vessel walls by
inflammation. Approximately half of
vasculitis cases are idiopathic, but sometimes associated with genetic factors, medicines,
chronic infection,
autoimmune diseases, and
malignancies. Although the mechanism remains unclear,
vasculitis secondary to
malignancy, also known as paraneoplastic
vasculitis, has been reported. It is generally associated with
hematologic malignancies rather than solid
malignancies and commonly presents as leukocytoclastic
vasculitis or
polyarteritis nodosa. We experienced a case of leukocytoclastic
vasculitis in a
patient with
hepatocellular carcinoma and membranous obstruction of the
inferior vena cava. Here, we
report this case with a brief
review of
literature.