Hypereosinophilic syndrome (HES) is characterized by persistent
eosinophilia associated with damage to multiple organs. Although the diagnostic criteria for HES include sustained
hypereosinophilia for at least 6 months, early initiation of
therapy may be recommended in
patients exhibiting HES symptoms. Eosinophilic
enteritis has been reported as a cause of
intussusception in several cases. However, HES as a cause of
intussusception has not yet been reported. In the present
report, we describe a case of HES that manifested as jejunojejunal
intussusception. Although long-standing
hypereosinophilia was not confirmed, the
patient required
eosinophil-lowering
therapy for an
intestinal obstruction. The
patient was treated with systemic
corticosteroids, after which the symptoms and multiple organ involvement, including
intussusception, improved dramatically, as noted on the radiological investigation. Moreover,
surgery was not necessary.