Lymphoepithelioma-like
carcinoma (LELC) of the
uterine cervix, also called lymphoepithelioma or
medullary carcinoma, is a very rare variant of
squamous cell carcinoma. Histologically, the
tumor is characterized by groups and nests of poorly differentiated
tumor cells with abundant
cytoplasm and ill-defined
cell borders, surrounded by an intense chronic inflammatory infiltrate.
Epstein-Barr virus (
EBV) may be involved in the development of LELC but the exact
role remains unclear. The relationship between
human papillomavirus (HPV) and LELC of the
uterine cervix has also not been reported. The
prognosis of LELC of the
uterine cervix seems to be better than that of cervical
squamous cell carcinoma. We
report a case of LELC of the
uterine cervix with a brief
review.