Selective intestinal
decontamination (
SID) with
norfloxacin has been widely used for the prophylaxis of spontaneous bacterial
peritonitis (SBP) because of a high
recurrence rate and preventive effect of
SID for SBP. However, it does select resistant
gut flora and may
lead to SBP caused by unusual pathogens such as
quinolone-resistant gram-negative bacilli or
gram-positive cocci.
Enterococcus hirae is known to cause
infections mainly in
animals, but is rarely encountered in
humans. We
report the first case of SBP by E. hirae in a cirrhotic
patient who have previously received an
oral administration of
norfloxacin against SBP caused by
Klebsiella pneumoniae and presented in
septic shock.