Hypereosinophilic syndrome (HES) has three defining features marked
hypereosinophilia for at least 6 months, no confirmed
etiology for the
eosinophilia, and
eosinophilia-related symptoms or organ dysfunction. However, a shorter period of
hypereosinophilia with symptoms requiring
eosinophil-lowering
therapy is also acceptable. We
report a case of HES presenting as eosinophilic
colitis. Although
hypereosinophilia was present for 3 months, this
patient needed to be treated with eosionphil-lowering
therapy for severe
hematochezia. After systemic
corticosteroid therapy, symptoms caused by organ involvement were dramatically improved.