Acute
mesenteric venous thrombosis (MVT) is an uncommon form of intestinal
ischemia with high
mortality and usually occurs in the setting of preexisting comorbidities including
thrombophilia and abdominal inflammatory conditions.
Hyperhomocysteinemia has been known to be a
risk factor for
thromboembolism, often located on an unusual site. Considering that
homocysteine metabolism is determined genetically to a high degree, a mutant of
methylenetetrahydrofolate reductase (MTHFR) C677T causes
hyperhomocysteinemia, leading to
thrombophilia. Until now, there have been few
reports of MVT associated with MTHFR
gene mutation. We, herein,
report a case of small bowel
infarction associated with MVT by MTHFR
gene mutation in an
adult without any other
risk factors of
thrombophilia.